BDBM416548 US10307425, Example 14::US10632122, Example 14

SMILES CN1CCC(Cn2nc(-c3ccc4cc(OCC(C)(C)O)ccc4c3)c3c(N)ncnc23)CC1

InChI Key InChIKey=RXTBOWBIOOJHHA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 416548   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM416548(US10307425, Example 14 | US10632122, Example 14)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant Toxoplasma gondii CDPK1 using Biotin-C6-PLARTLSVAGLPGKK as substrate after 90 mins in presence of ATP by luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM416548(US10307425, Example 14 | US10632122, Example 14)
Affinity DataIC50:  24.2nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent